Cosmonauts of the Russian space agency Roscosmos Oleg Artemyev, Denis Matveyev and Sergei Korsakov successfully took off from the Russian cosmodrome Baikonur in Kazakhstan in the Soyuz MS-21 spacecraft.
They arrived at the station after just over three hours, joining a seven-member crew consisting of two Russians, four Americans and one German.
This is the first launch of a space crew since Russia invaded Ukraine on February 24. Due to the war, spacecraft launches were canceled and contracts were terminated.
NASA Administrator Bill Nelson told the Associated Press that there is still cooperation with Russian cosmonauts from the civilian space program.
NASA astronaut Mark Vande Hay, who broke the American record in one space flight of 340 days on Tuesday, is due to leave the International Space Station with two Russians in a Soyuz capsule that will land in Kazakhstan on March 30.
In April, three more NASA astronauts and one Italian astronaut are scheduled to fly to the space station.